Today’s re-blog as part of World Alzheimer’s Month focuses on an article by Susan Macaulay which comments on 20 behavioural expressions for which antipsychotic medications are unwarranted and ineffective in people who live with Dementia.

“What happens in the brain chemically–even when people are labeled “delusional”–is not the same in diseases that cause dementia as in classical psychosis where dopamine activity is increased, causing hallucinations and delusions. The primary action [of antipsychotics]in that disorder is achieved by blocking dopamine activity.

But no form of dementia involves heightened dopamine activity; in fact many people, including those with Lewy body dementia, have decreased dopamine activity. So dopamine-blocking drugs not only have no chemical rationale, they also are particularly toxic for such people.”

20 behavioural expressions for which antipsychotic medications are unwarranted and ineffective in people who live with dementia